Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 2/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NMBR | P28336 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158577 | 0.86 | CTSS (0.51) | CTSLCTSSCTSK | |
| SCHEMBL23177644 | 0.86 | CTSL (0.54) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL23158632 | 0.85 | TTR (0.50) | CTSSCTSK | |
| SCHEMBL23177649 | 0.85 | TTR (0.50) | CTSSCTSK | |
| SCHEMBL23158641 | 0.84 | HDAC8 (0.51) | MAPTTERTSMN1; SMN2ACHEBCHE | |
| SCHEMBL23158592 | 0.82 | TTR (0.54) | — | |
| SCHEMBL23158797 | 0.82 | TTR (0.46) | CTSSCTSK | |
| SCHEMBL23158581 | 0.81 | TTR (0.45) | CTSSCTSK | |
| SCHEMBL23177646 | 0.81 | TTR (0.45) | CTSSCTSK | |
| SCHEMBL23158609 | 0.81 | TTR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021060351-A1 | NSAID-BONDED ALGINIC ACID DERIVATIVE | 持田製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |