Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AOC2 | O75106 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARL | Q9H300 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222219 | 0.85 | ALDH1A1 (0.42) | FFAR2MAPK1AOC2MAOANPSR1 | |
| SCHEMBL4347000 | 0.85 | ALDH1A1 (0.42) | FFAR2MAPK1AOC2MAOANPSR1 | |
| SCHEMBL21037193 | 0.85 | AOC2 (0.40) | FFAR2MCHR1PRMT5WDR77NAMPT | |
| SCHEMBL10171748 | 0.85 | ALDH1A1 (0.42) | FFAR2MAPK1AOC2MAOANPSR1 | |
| SCHEMBL12816496 | 0.81 | PKM (0.40) | FFAR2MCHR1PRMT5WDR77NPSR1 | |
| SCHEMBL12816499 | 0.81 | KMT2A (0.41) | FFAR2MCHR1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL20751552 | 0.79 | AOC2 (0.50) | FFAR2GBA1NAMPTAOC2MAOA | |
| SCHEMBL15929766 | 0.79 | AOC2 (0.50) | FFAR2GBA1NAMPTAOC2MAOA | |
| SCHEMBL6556991 | 0.78 | GBA1 (0.43) | FFAR2GBA1MAPK1NPSR1PARL | |
| SCHEMBL28184784 | 0.77 | ALDH1A1 (0.44) | FFAR2GBA1MAPK1PARLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3587420-B1 | TRI-CYCLE COMPOUND AND APPLICATIONS THEREOF | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2021-03-31 | — | — | EP | disclosed |