Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17069297 | 0.86 | ACP3 (0.46) | ALDH1A1ACP3TSHRHPGD | |
| SCHEMBL19117766 | 0.83 | TSHR (0.52) | IDO1TDO2CNR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL409949 | 0.83 | TSHR (0.52) | IDO1TDO2CNR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5029899 | 0.82 | RIPK1 (0.43) | TSHRLMNA | |
| SCHEMBL20747579 | 0.79 | AOC3 (0.45) | ALDH1A1SMN1; SMN2ACP3TSHR | |
| SCHEMBL17069273 | 0.77 | IDO1 (0.49) | IDO1TDO2 | |
| SCHEMBL17069244 | 0.73 | IDO1 (0.47) | IDO1TDO2CNR2TACR1CNR1 | |
| SCHEMBL23843796 | 0.73 | TSHR (0.61) | IDO1TDO2ALDH1A1TSHRLMNA | |
| SCHEMBL17069289 | 0.72 | IDO1 (0.50) | IDO1TDO2CNR2TACR1ALDH1A1 | |
| SCHEMBL17069291 | 0.72 | IDO1 (0.50) | IDO1TDO2CNR2TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | BRIX1, RDX, SULT2A1 | IDO1 2403/4885TDO2 3264/4885CNR2 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.