Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316139 | 1.00 | ITGB1 (0.50) | ITGB1ITGA4MMEMMEL1MEN1 | |
| SCHEMBL2318219 | 0.87 | MME (0.50) | MMEMMEL1MEN1KMT2AGAA | |
| SCHEMBL2318230 | 0.87 | MME (0.50) | MMEMMEL1MEN1KMT2AGAA | |
| SCHEMBL2318924 | 0.86 | MME (0.58) | ITGB1ITGA4MMEMMEL1MEN1 | |
| SCHEMBL2318931 | 0.86 | MME (0.58) | ITGB1ITGA4MMEMMEL1MEN1 | |
| SCHEMBL2315959 | 0.81 | TAAR1 (0.62) | MMEMMEL1MEN1KMT2AGAA | |
| SCHEMBL2315968 | 0.81 | TAAR1 (0.62) | MMEMMEL1MEN1KMT2AGAA | |
| SCHEMBL2316457 | 0.78 | LMNA (0.55) | ITGB1ITGA4MMEMMEL1MEN1 | |
| SCHEMBL2316474 | 0.78 | LMNA (0.55) | ITGB1ITGA4MMEMMEL1MEN1 | |
| SCHEMBL2317678 | 0.77 | MME (0.60) | ITGB1ITGA4MMEMMEL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |