Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL19859034 | 1.00 | CYP2C9 (0.33) | CYP2C9CYP2C19TDP1 | |
| SCHEMBL27432894 | 0.88 | ADH1B (0.32) | — | |
| SCHEMBL30160 | 0.88 | — | — | |
| SCHEMBL28297084 | 0.87 | DNM1 (0.48) | TDP1 | |
| Hydrochloric Acid SCHEMBL28400231 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL4441190 | 0.85 | — | — | |
| Fluoride SCHEMBL9160415 | 0.85 | — | — | |
| Iodide SCHEMBL28709678 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL8476165 | 0.85 | — | — | |
| Hydrogen Sulfide SCHEMBL16226309 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8496716-B2 | Method for producing Mannich adducts that contain polyisobutylene phenol | BASF SE (DE) | 2013-07-30 | — | — | US | disclosed |
| US-20110251114-A1 | METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL | BASF SE (DE) | 2011-10-13 | — | — | US | disclosed |
| US-8016898-B1 | Method for producing Mannich adducts that contain polyisobutylene phenol | BASF AKTIENGESELLSCHAFT (DE) | 2011-09-13 | — | — | US | disclosed |
| US-7988749-B2 | Method for producing Mannich adducts that contain polyisobutylene phenol | BASF SE (DE) | 2011-08-02 | — | — | US | disclosed |
| US-20080274924-A1 | Alkylation of a phenol with polyisobutylene at low temperature in presence of alkylation catalyst; then formaldehyde and amine; oil and fuel additive | BASF AKTIENGESELLSCHAFT (DE) | 2008-11-06 | — | — | US | disclosed |
| US-20050268539-A1 | Additive mixture for fuel and lubricants | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251114-A1 | METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL | ADH1C, FANCF, PCNA | CYP2C9 2347/4885CYP2C19 2247/4885TDP1 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.