Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.53 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316070 | 1.00 | FFAR2 (0.53) | FFAR2PIN1FDFT1MMENR1H4 | |
| SCHEMBL2316077 | 1.00 | FFAR2 (0.53) | FFAR2PIN1FDFT1MMENR1H4 | |
| SCHEMBL2320587 | 0.92 | FFAR2 (0.58) | FFAR2FDFT1MMEMMEL1S1PR3 | |
| SCHEMBL2320594 | 0.92 | FFAR2 (0.58) | FFAR2FDFT1MMEMMEL1S1PR3 | |
| SCHEMBL2314462 | 0.88 | PIN1 (0.57) | FFAR2PIN1MMENR1H4MMEL1 | |
| SCHEMBL2317481 | 0.88 | PIN1 (0.57) | FFAR2PIN1MMENR1H4MMEL1 | |
| SCHEMBL2316350 | 0.88 | FFAR2 (0.61) | FFAR2PIN1MMENR1H4MMEL1 | |
| SCHEMBL2316357 | 0.88 | FFAR2 (0.61) | FFAR2PIN1MMENR1H4MMEL1 | |
| SCHEMBL2314452 | 0.88 | PIN1 (0.57) | FFAR2PIN1MMENR1H4MMEL1 | |
| SCHEMBL2315069 | 0.88 | PIN1 (0.59) | FFAR2PIN1MMENR1H4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |