Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23204566 | 0.84 | BTK (0.34) | BTKF2RL3 | |
| SCHEMBL21273294 | 0.76 | SUV39H2 (0.33) | IKBKETBK1BTKF2RL3 | |
| SCHEMBL23305873 | 0.76 | SNCA (0.31) | IKBKETBK1F2RL3 | |
| SCHEMBL23389317 | 0.74 | CCNE1 (0.43) | USP30 | |
| SCHEMBL19984740 | 0.74 | F2RL3 (0.32) | F2RL3 | |
| SCHEMBL29045759 | 0.72 | TBK1 (0.44) | IKBKETBK1BTK | |
| SCHEMBL23164588 | 0.69 | ALDH1A1 (0.33) | IKBKETBK1 | |
| SCHEMBL19984739 | 0.68 | — | — | |
| SCHEMBL26605652 | 0.68 | SUV39H2 (0.33) | IKBKETBK1F2RL3 | |
| SCHEMBL629668 | 0.67 | PDPK1 (0.32) | IKBKETBK1F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124489-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-04-18 | — | — | US | disclosed |
| US-20230139171-A1 | SYSTEM AND METHOD FOR INSTRUCTING ONE OR MORE WEATHER DRONES | SITA INFORMATION NETWORKING COMPUTING UK LIMITED (GB) | 2023-05-04 | — | — | US | disclosed |
| WO-2021067326-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124489-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | TLR7, TLR1, TLR9 | IKBKE 322/4885TBK1 284/4885BTK 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.