Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21973186 | 0.85 | KMT2A (0.44) | KMT2AL3MBTL1AKT1ALDH1A1MEN1 | |
| SCHEMBL30835192 | 0.85 | KMT2A (0.44) | KMT2AL3MBTL1AKT1ALDH1A1MEN1 | |
| SCHEMBL21166309 | 0.84 | KMT2A (0.59) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL28352519 | 0.83 | KMT2A (0.58) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL13841915 | 0.80 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL8869835 | 0.80 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL2821018 | 0.80 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL9308794 | 0.80 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL8566009 | 0.80 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL16022317 | 0.80 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094912-A1 | INDOLE DERIVATIVES AS EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094912-A1 | INDOLE DERIVATIVES AS EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, ABCG2 | KMT2A 4541/4885L3MBTL1 4699/4885BRD4 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.