Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166309 | 0.90 | KMT2A (0.59) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL2821018 | 0.85 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL16022317 | 0.85 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL13841915 | 0.85 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL9308794 | 0.85 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL8566009 | 0.85 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL8869835 | 0.85 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL23167435 | 0.83 | KMT2A (0.53) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL20494615 | 0.83 | SIGMAR1 (0.40) | KMT2AL3MBTL1DRD2MAPT | |
| SCHEMBL13841916 | 0.83 | KMT2A (0.59) | KMT2AL3MBTL1KDM1AMAOBKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770224-B | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-110770224-A | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2020-02-07 | — | — | CN | disclosed |