⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304992 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL303118 | 0.97 | — | — | |
| SCHEMBL2565171 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL577753 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL577732 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL3386412 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL59455 | 0.97 | — | — | |
| SCHEMBL2564589 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL9219931 | 0.97 | TSHR (0.53) | — | |
| SCHEMBL302707 | 0.97 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233786-B | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-11-26 | — | — | CN | claimed |
| CN-111233786-A | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-06-05 | — | — | CN | claimed |
| CN-110272355-A | Azobenzene derivatives and its manufacturing method | 捷恩智株式会社 | 2019-09-24 | — | — | CN | claimed |
| EP-2609101-B1 | PROCESS FOR THE PREPARATION OF 3-(N-METHYL-N-PENTYL)AMINO-1-HYDROXYPROPANE-1,1-DIPHOSPHONIC ACID SALT OR DERIVATIVES THEREOF | PHARMATHEN SA (GR) | 2015-01-28 | — | — | EP | claimed |
| EP-2460800-A1 | Substituted aminothiazole derivatives with anti-HCV activity | Achillion Pharmaceuticals, Inc. (US) | 2012-06-06 | — | — | EP | claimed |
| CN-100522128-C | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2009-08-05 | — | — | CN | claimed |
| US-20070213301-A1 | Substituted Aminothiazole Derivatives With Anti-HCV Activity | ACHILLION PHARMACEUTICALS, INC. (US) | 2007-09-13 | — | — | US | claimed |
| CN-101010060-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-08-01 | — | — | CN | claimed |
| CN-101010118-A | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2007-08-01 | — | — | CN | claimed |
| CN-101010061-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-08-01 | — | — | CN | claimed |
| US-6255288-B1 | THERAPY FOR BONE DISORDERS | NOVARTIS CORPORATION | 2001-07-03 | — | — | US | claimed |
| EP-1021417-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2000-07-26 | — | — | EP | claimed |
| WO-1999012913-A1 | SUBSTITUTED PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | claimed |
| WO-1997016449-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | claimed |
| EP-0600834-A1 | Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| US-5296475-A | Methanediphosphonic acids and crown compounds for treatment of bone disorders or hypercalcemia | CIBA-GEIGY CORPORATION (US) | 1994-03-22 | — | — | US | claimed |
| EP-0550385-A1 | Oral pharmaceutical compositions containing derivatives of methane-diphosphonic acid and 18-crown-6 ethers | CIBA-GEIGY AG (CH) | 1993-07-07 | — | — | EP | claimed |
| EP-0407344-A2 | Pharmaceutical preparation for topical application | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | claimed |
| EP-0279781-A2 | Process for the preparation of 4-acetoxy-3-hydroxyethyl-acetidinone | CIBA-GEIGY AG (CH) | 1988-08-24 | — | — | EP | claimed |
| US-3933786-A | Heterocyclic-azo-phenyl compounds containing a styrl group | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | claimed |