Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | FPR2 | P25090 | 13/20 | 0.45 |
| ▸ | FPR1 | P21462 | 7/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168328 | 1.00 | F10 (0.46) | F10FPR2FPR1USP30HRH3 | |
| SCHEMBL18964307 | 0.88 | FPR2 (0.53) | F10FPR2FPR1 | |
| SCHEMBL21900482 | 0.86 | FPR2 (0.41) | F10FPR2FPR1USP30 | |
| SCHEMBL28376667 | 0.86 | FPR2 (0.41) | F10FPR2FPR1USP30 | |
| SCHEMBL22820700 | 0.84 | FPR2 (0.41) | F10FPR2FPR1 | |
| SCHEMBL20581623 | 0.84 | FPR2 (0.46) | F10FPR2FPR1 | |
| SCHEMBL20581625 | 0.84 | FPR2 (0.46) | F10FPR2FPR1 | |
| SCHEMBL27594883 | 0.84 | AAK1 (0.40) | F10FPR2FPR1USP30HRH3 | |
| SCHEMBL18963928 | 0.83 | FPR2 (0.48) | F10FPR2FPR1 | |
| SCHEMBL18963926 | 0.83 | FPR2 (0.48) | F10FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997652-B | Piperidinone formyl peptide 2 receptor agonists | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | disclosed |
| EP-3634955-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-31 | — | — | EP | disclosed |
| CN-110997652-A | Piperidinone formyl peptide 2 receptor agonists | 百时美施贵宝公司 | 2020-04-10 | — | — | CN | disclosed |