Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.35 |
| ▸ | SDHB | P21912 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168751 | 0.87 | NPBWR1 (0.37) | P2RX7NPBWR1SDHBLMNACYP1A2 | |
| SCHEMBL24819258 | 0.86 | NPBWR1 (0.39) | P2RX7NPBWR1SDHBALDH1A1POLB | |
| SCHEMBL23168941 | 0.85 | THRB (0.38) | P2RX7NPBWR1LMNACYP1A2CYP3A4 | |
| SCHEMBL29821988 | 0.85 | NPBWR1 (0.48) | P2RX7NPBWR1LMNACYP1A2CYP3A4 | |
| SCHEMBL24819271 | 0.85 | NPBWR1 (0.48) | P2RX7NPBWR1LMNACYP1A2CYP3A4 | |
| SCHEMBL23168772 | 0.85 | MAPT (0.43) | P2RX7NPBWR1LMNACYP1A2CYP3A4 | |
| SCHEMBL23168950 | 0.84 | P2RX7 (0.40) | P2RX7LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29822173 | 0.84 | P2RX7 (0.40) | P2RX7LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23168932 | 0.84 | NPBWR1 (0.43) | NPBWR1SDHBLMNAKDM4EALDH1A1 | |
| SCHEMBL23168653 | 0.80 | MAPT (0.47) | P2RX7NPBWR1SDHBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057791-A1 | CHEMICAL COMPOUND AS THYROID HORMONE BETA RECEPTOR AGONIST AND USE THEREOF | 广东东阳光药业有限公司 | 2021-04-01 | — | — | WO | disclosed |