Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396334 | 0.93 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL2320213 | 0.91 | HTR1A (0.32) | KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL2315170 | 0.90 | MAOB (0.37) | KDM4EALDH1A1KMT2A | |
| SCHEMBL14135216 | 0.90 | KMT2A (0.38) | KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL12432834 | 0.90 | KMT2A (0.38) | KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL2316234 | 0.90 | KMT2A (0.38) | KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL2315691 | 0.90 | — | — | |
| SCHEMBL2316977 | 0.90 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL2313970 | 0.89 | KCNH2 (0.31) | — | |
| SCHEMBL2316454 | 0.87 | LTA4H (0.33) | KDM4EALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | claimed |