Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4406781 | 0.93 | MAOB (0.34) | KDM4EALDH1A1HSD17B10MCHR1DRD2 | |
| SCHEMBL2316892 | 0.93 | KDM4E (0.31) | KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4406815 | 0.92 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10MCHR1DRD2 | |
| SCHEMBL4396521 | 0.91 | DRD2 (0.36) | DRD2DRD3HTR2AMAOB | |
| SCHEMBL4398647 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1HSD17B10MCHR1HPGD | |
| Hydrochloric Acid SCHEMBL4406708 | 0.90 | HTR1A (0.35) | KDM4EALDH1A1HSD17B10MCHR1DRD2 | |
| SCHEMBL914445 | 0.89 | KMT2A (0.40) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL4410352 | 0.89 | KDM4E (0.35) | KDM4EALDH1A1DRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL4403444 | 0.89 | HTR7 (0.31) | ALDH1A1MCHR1DRD2KMT2A | |
| Hydrochloric Acid SCHEMBL4401793 | 0.88 | FAAH (0.32) | ALDH1A1MCHR1MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |