SCHEMBL23170959

SCHEMBL23170959

Cc1ccccc1-c1ncnc2ccsc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 0.46
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
PDE3B Q13370 1/20 0.42
PDE3A Q14432 1/20 0.42
ADORA2A P29274 4/20 0.40
ADORA2B P29275 1/20 0.40
CYP1A2 P05177 8/20 0.39
CYP3A4 P08684 5/20 0.39
CLK4 Q9HAZ1 5/20 0.39
TSHR P16473 4/20 0.39
ALDH1A1 P00352 4/20 0.39
MAPK1 P28482 3/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21128382 0.80 MAPK13 (0.46) ADORA2ACYP1A2CYP3A4CLK4TSHR
SCHEMBL23170958 0.78 AXL (0.41) AXLMKNK1MKNK2PDE4APDE4B
SCHEMBL4828004 0.76 ADORA2A (0.52) AXLMKNK1MKNK2PDE4APDE4B
SCHEMBL21303016 0.75 AXL (0.51) AXLMKNK1MKNK2PDE4APDE4B
SCHEMBL23503946 0.74 SCN9A (0.46) ADORA2ACYP1A2CYP3A4TSHRALDH1A1
SCHEMBL22342528 0.73 AXL (0.49) AXLMKNK1MKNK2PDE4APDE4B
SCHEMBL18921234 0.73 CDK5 (0.44) CYP1A2CYP3A4CLK4TSHRALDH1A1
SCHEMBL2129016 0.73 ALDH1A1 (0.43) ADORA2ACYP1A2CYP3A4CLK4TSHR
SCHEMBL19258239 0.73 ADORA2A (0.56) PDE4APDE4BPDE4CPDE4DADORA2A
SCHEMBL29403276 0.73 ALDH1A1 (0.43) ADORA2ACYP1A2CYP3A4CLK4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210094978-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210094978-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 AXL 3030/4885MKNK1 3439/4885MKNK2 3390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.