SCHEMBL4828004

SCHEMBL4828004

c1ccc(-c2ncnc3ccsc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.52
AXL P30530 1/20 0.52
MKNK1 Q9BUB5 1/20 0.52
MKNK2 Q9HBH9 1/20 0.52
PDE4A P27815 1/20 0.50
PDE4B Q07343 1/20 0.50
PDE4C Q08493 1/20 0.50
PDE4D Q08499 1/20 0.50
PDE3B Q13370 1/20 0.50
PDE3A Q14432 1/20 0.50
CAMKK1 Q8N5S9 1/20 0.47
CAMKK2 Q96RR4 1/20 0.47
PDK1 Q15118 2/20 0.46
MAPT P10636 1/20 0.41
PDPK1 O15530 1/20 0.41
HTR2C P28335 1/20 0.41
FADS1 O60427 1/20 0.40
AURKA O14965 1/20 0.40
AURKB Q96GD4 1/20 0.40
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22342528 0.82 AXL (0.49) ADORA2AAXLMKNK1MKNK2PDE4A
SCHEMBL3983932 0.80 MAP4K4 (0.47) AXLMKNK1MKNK2PDE4APDE4B
SCHEMBL22342533 0.78 AXL (0.45) AXLMKNK1MKNK2PDE4APDE4B
SCHEMBL24795210 0.77 AXL (0.47) ADORA2AAXLMKNK1MKNK2PDE4A
SCHEMBL22442100 0.77 AXL (0.47) ADORA2AAXLMKNK1MKNK2PDE4A
SCHEMBL3681709 0.77 ADORA1 (0.57) ADORA2AAXLMKNK1MKNK2PDE4A
SCHEMBL22342531 0.77 NTRK1 (0.45) ADORA2AAXLMKNK1MKNK2CAMKK1
SCHEMBL23170959 0.76 AXL (0.46) ADORA2AAXLMKNK1MKNK2PDE4A
SCHEMBL24795754 0.75 LIMK1 (0.40) ADORA2APDE4APDE4BPDE4CPDE4D
SCHEMBL22342532 0.72 ADORA2A (0.61) ADORA2AAXLMKNK1MKNK2PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-08-10 US disclosed
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed
US-11325932-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-10 US disclosed
US-20200283462-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION, 2020-09-10 US disclosed
US-20190207127-A1 ORGANIC METAL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICES EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2019-07-04 US disclosed
US-7438980-B2 Organometallic complex and organic electroluminescent devices utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2008-10-21 US disclosed
US-7438980-B2 Organometallic complex and organic electroluminescent devices utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2008-10-21 US disclosed
US-7438980-B2 Organometallic complex and organic electroluminescent devices utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2008-10-21 US disclosed
US-20060134462-A1 Organometallic complex and organic electroluminescent devices utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2006-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB ADORA2A 4188/4885AXL 1849/4885MKNK1 1611/4885
US-20200283462-A1 Organic Electroluminescent Materials and Devices L1CAM, KCNN4, ITGB4 ADORA2A 2584/4885AXL 1350/4885MKNK1 1976/4885
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF CRY1, LEF1, PIEZO1 ADORA2A 2755/4885AXL 3099/4885MKNK1 982/4885
US-11325932-B2 Organic electroluminescent materials and devices L1CAM, RTN4, KCNN4 ADORA2A 1583/4885AXL 990/4885MKNK1 1673/4885
US-20190207127-A1 ORGANIC METAL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICES EMPLOYING THE SAME APOL1, MSL1, MRPS22 ADORA2A 4246/4885AXL 1627/4885MKNK1 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.