Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364031 | 0.87 | RARB (0.40) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL2310945 | 0.79 | RARB (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL2314604 | 0.79 | RARB (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL6003914 | 0.76 | ALOX5 (0.31) | MEN1ALDH1A1MAPTKMT2ATP53 | |
| SCHEMBL2317651 | 0.75 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27872843 | 0.74 | ALOX5 (0.30) | MEN1ALDH1A1MAPTKMT2ATP53 | |
| SCHEMBL7262706 | 0.72 | TLR8 (0.32) | MEN1ALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL28930126 | 0.71 | BCL2L1 (0.33) | ALDH1A1NPC1RAB9ACSNK2A2CSNK2A1 | |
| SCHEMBL1673815 | 0.70 | ALDH1A1 (0.40) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL28089246 | 0.70 | BCL2L1 (0.33) | ALDH1A1NPC1RAB9ACSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350058-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033678-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |