Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2342869 | 0.77 | MAPT (0.43) | MAPTSMN1; SMN2TLR8MGLLCYP4F2 | |
| SCHEMBL2318543 | 0.77 | MAPT (0.43) | MAPTSMN1; SMN2TLR8MGLLCYP4F2 | |
| SCHEMBL2319620 | 0.77 | MAPT (0.43) | MAPTSMN1; SMN2TLR8MGLLCYP4F2 | |
| SCHEMBL2317204 | 0.75 | RARB (0.38) | MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7261873 | 0.73 | MAPT (0.38) | MAPTSMN1; SMN2TLR8NPC1RAB9A | |
| SCHEMBL2364031 | 0.73 | RARB (0.40) | MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6003914 | 0.72 | ALOX5 (0.31) | MAPT | |
| SCHEMBL7262706 | 0.70 | TLR8 (0.32) | MAPTSMN1; SMN2TLR8RAB9A | |
| SCHEMBL585686 | 0.68 | PTGS2 (0.35) | — | |
| SCHEMBL23909136 | 0.67 | SETD7 (0.46) | MAPTSMN1; SMN2NPC1RAB9ASETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350058-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033678-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |