Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762477 | 0.88 | HTT (0.59) | MEN1KMT2AALOX5POLBHTT | |
| SCHEMBL27776291 | 0.86 | ALOX5 (0.56) | MEN1KMT2AALOX5POLBHTT | |
| SCHEMBL6161137 | 0.85 | MEN1 (0.62) | MEN1KMT2AALOX5POLBSMN1; SMN2 | |
| SCHEMBL561284 | 0.83 | HTT (0.64) | MEN1KMT2AALOX5POLBHTT | |
| SCHEMBL1025493 | 0.82 | HTT (0.53) | MEN1KMT2AALOX5POLBHTT | |
| SCHEMBL29735373 | 0.82 | HTT (0.53) | MEN1KMT2AALOX5POLBHTT | |
| SCHEMBL229926 | 0.81 | MEN1 (0.57) | MEN1KMT2AALOX5POLBHTT | |
| Methyl 3,5-Dinitrobenzoate SCHEMBL418416 | 0.80 | SMN1; SMN2 (0.60) | MEN1KMT2AALOX5POLBHTT | |
| SCHEMBL233571 | 0.79 | MEN1 (0.55) | MEN1KMT2APOLBHTTSMN1; SMN2 | |
| SCHEMBL4236814 | 0.79 | POLB (0.73) | MEN1KMT2AALOX5POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341371-A | As LTC4Bis-aromatic compounds as synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-01 | — | — | CN | disclosed |
| EP-2406220-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | Biolipox AB (SE) | 2012-01-18 | — | — | EP | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| WO-2010103279-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LCT4 SYNTHASE INHIBITORS | BIOLIPOX AB (SE) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | MEN1 4355/4885KMT2A 4283/4885ALOX5 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.