Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18551939 | 1.00 | MEN1 (0.35) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16557254 | 0.83 | MEN1 (0.35) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26288674 | 0.81 | MEN1 (0.34) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22844076 | 0.81 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18551965 | 0.81 | CES2 (0.44) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20231183 | 0.81 | CES2 (0.44) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24484030 | 0.78 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22940370 | 0.77 | GLP1R (0.34) | MEN1KMT2A | |
| SCHEMBL16557168 | 0.75 | CA2 (0.41) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20706169 | 0.74 | CES2 (0.34) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021058017-A1 | DEGRADATION OF ANDROGEN RECEPTOR (AR) BY CONJUGATION OF AR ANTAGONISTS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2021-04-01 | — | — | WO | disclosed |