SCHEMBL22844076

SCHEMBL22844076

CNCCOCCOCC(=O)I

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20706169 0.88 CES2 (0.34) MEN1KMT2ASMN1; SMN2
SCHEMBL22297128 0.86 CYP2C19 (0.37) MEN1KMT2ASMN1; SMN2
SCHEMBL20353236 0.83 MEN1 (0.38) MEN1KMT2ASMN1; SMN2
SCHEMBL22340971 0.81 CES2 (0.45) MEN1KMT2ASMN1; SMN2
SCHEMBL13553383 0.81 CES2 (0.45) MEN1KMT2ASMN1; SMN2
SCHEMBL23173307 0.81 MEN1 (0.35) MEN1KMT2ASMN1; SMN2
SCHEMBL24309097 0.81 CYP2C19 (0.41) MEN1KMT2ASMN1; SMN2
SCHEMBL12139725 0.81 CYP2C19 (0.41) MEN1KMT2ASMN1; SMN2
SCHEMBL12237951 0.81 CYP2C19 (0.41) MEN1KMT2ASMN1; SMN2
SCHEMBL20322404 0.81 CES2 (0.45) MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239852-A1 AMYLIN RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2024-07-18 US disclosed
US-20200407409-A1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS CHEN JIANHE (CN) 2020-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239852-A1 AMYLIN RECEPTOR AGONISTS GLP1R, GPR119, GIPR MEN1 828/4885KMT2A 4387/4885SMN1; SMN2 1601/4885
US-20200407409-A1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS EGFR, LDLR, FFAR2 MEN1 3956/4885KMT2A 3113/4885SMN1; SMN2 4619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.