SCHEMBL23174355

SCHEMBL23174355

CCS(=O)(=O)c1ccc(-c2c(Cl)cc(NC(=O)Cc3ccc(S(C)(=O)=O)cc3)cc2Cl)cc1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23174426 1.00 RORC (0.81) RORC
SCHEMBL23174348 0.95 RORC (0.89) RORC
SCHEMBL23174347 0.94 RORC (0.71) RORC
SCHEMBL23193328 0.90 RORC (0.67) RORC
SCHEMBL14754270 0.90 RORC (0.80) RORC
SCHEMBL14754254 0.90 RORC (1.00) RORC
SCHEMBL23174412 0.89 RORC (0.64) RORC
SCHEMBL23174415 0.88 RORC (0.64) RORC
SCHEMBL23193667 0.88 RORC (0.81) RORC
SCHEMBL22664418 0.88 RORC (1.00) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402867-A1 SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF SHANGHAI LITEDD CO., LTD. (CN) 2022-12-22 US disclosed
WO-2021063362-A1 SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海辉启生物医药科技有限公司 2021-04-08 WO disclosed
WO-2021063362-A1 SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海辉启生物医药科技有限公司 2021-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402867-A1 SULFO-SUBSTITUTED BIARYL COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF RORB, RORA, RORC RORC 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.