SCHEMBL2317461

SCHEMBL2317461

C=C(c1ccccc1)c1c(C(=O)O)ccnc1-c1cc(C(=O)O)ccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 11/20 0.52
KDM5C P41229 9/20 0.52
KDM4A O75164 8/20 0.52
KDM4E B2RXH2 5/20 0.52
KDM2A Q9Y2K7 5/20 0.52
KDM3A Q9Y4C1 5/20 0.52
KDM6B O15054 4/20 0.52
P4HA1 P13674 1/20 0.44
KDM2B Q8NHM5 2/20 0.44
KDM5B Q9UGL1 9/20 0.43
KDM4B O94953 4/20 0.43
KDM5A P29375 5/20 0.42
JMJD6 Q6NYC1 1/20 0.42
KMO O15229 1/20 0.42
TET3 O43151 1/20 0.41
BBOX1 O75936 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
ASPH Q12797 1/20 0.41
KDM4D Q6B0I6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528803 0.77 KDM4C (0.53) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL7952527 0.76 KDM4C (0.53) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL17220133 0.76 KDM4C (0.51) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL7965043 0.75 KDM4C (0.51) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL2315594 0.74 KDM5C (0.57) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL2317463 0.74 KDM4C (0.50) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL730406 0.73 KDM4C (0.49) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL7962908 0.72 KDM4C (0.50) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL10526279 0.72 KDM4C (0.49) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL87737 0.72 KDM4E (0.50) KDM4CKDM5CKDM4AKDM4EKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2353195-B9 PHOTOELECTRIC CONVERSION DEVICES COMPRISING NOVEL LIGANDS AND SENSITIZERS ECOLE POLYTECHNIQUE FED DE LAUSANNE EPFL EPFL TTO (CH) 2019-02-06 EP disclosed
EP-2353195-B1 PHOTOELECTRIC CONVERSION DEVICES COMPRISING NOVEL LIGANDS AND SENSITIZERS ECOLE POLYTECHNIQUE FED DE LAUSANNE EPFL EPFL TTO (CH) 2018-10-10 EP disclosed
US-8962977-B2 Photoelectric conversion devices comprising novel ligands and sensitizers ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2015-02-24 US disclosed
US-20110303267-A1 PHOTOELECTRIC CONVERSION DEVICES COMPRISING NOVEL LIGANDS AND SENSITIZERS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2011-12-15 US disclosed
EP-2353195-A1 PHOTOELECTRIC CONVERSION DEVICES COMPRISING NOVEL LIGANDS AND SENSITIZERS Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2011-08-10 EP disclosed
WO-2010055470-A1 PHOTOELECTRIC CONVERSION DEVICES COMPRISING NOVEL LIGANDS AND SENSITIZERS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110303267-A1 PHOTOELECTRIC CONVERSION DEVICES COMPRISING NOVEL LIGANDS AND SENSITIZERS CRY1, NECTIN4, PYCR1 KDM4C 698/4885KDM5C 1564/4885KDM4A 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.