Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317467 | 1.00 | MME (0.56) | MMEMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2315478 | 0.85 | MEN1 (0.70) | MMEMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2315472 | 0.85 | MEN1 (0.70) | MMEMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2314782 | 0.84 | HPGD (0.60) | MMEMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2319208 | 0.84 | MME (0.62) | MMEMEN1KMT2APOLBHTT | |
| SCHEMBL2314791 | 0.84 | HPGD (0.60) | MMEMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2319212 | 0.84 | MME (0.62) | MMEMEN1KMT2APOLBHTT | |
| SCHEMBL2317023 | 0.82 | MEN1 (0.51) | MMEMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2317033 | 0.82 | MEN1 (0.51) | MMEMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2317493 | 0.82 | FFAR2 (0.65) | MMEPOLBPKMFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |