Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106262 | 0.90 | ALDH1A1 (0.59) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL30281263 | 0.81 | ALDH1A1 (0.57) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL30366498 | 0.80 | ALDH1A1 (0.65) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL13730424 | 0.80 | LTA4H (0.48) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL28605800 | 0.78 | ALDH1A1 (0.50) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL28391873 | 0.78 | ALDH1A1 (0.54) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL30617050 | 0.78 | LTA4H (0.59) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL12495472 | 0.77 | NPSR1 (0.83) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL34461806 | 0.77 | ALDH1A1 (0.65) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM | |
| SCHEMBL1081345 | 0.76 | ALDH1A1 (0.53) | LMNASMN1; SMN2ALDH1A1CYP2D6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066088-A1 | NOVEL TRIAZINE DERIVATIVE | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2021-04-08 | — | — | WO | disclosed |