Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363470 | 0.90 | CYP2D6 (0.41) | GBA1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3885138 | 0.80 | HTR4 (0.33) | NPY5RALDH1A1PKM | |
| SCHEMBL17057613 | 0.78 | GBA1 (0.40) | GBA1TDP1PARGMCHR1ADRA2A | |
| SCHEMBL13770975 | 0.76 | SIGMAR1 (0.47) | MCHR1KMT2A | |
| SCHEMBL5519897 | 0.75 | CNR1 (0.39) | GBA1TDP1MCHR1ADRA2ANPY5R | |
| SCHEMBL26697611 | 0.75 | GBA1 (0.44) | GBA1TDP1PARGMCHR1ADRA2A | |
| SCHEMBL17039440 | 0.74 | MEN1 (0.39) | GBA1MCHR1ADRA2ANPY5RLMNA | |
| SCHEMBL4442555 | 0.73 | GBA1 (0.42) | GBA1TDP1PARGCNR2CNR1 | |
| SCHEMBL14626325 | 0.72 | MCHR1 (0.45) | MCHR1ADRA2ANPY5RLMNACNR2 | |
| SCHEMBL630853 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066088-A1 | NOVEL TRIAZINE DERIVATIVE | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2021-04-08 | — | — | WO | disclosed |