Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175142 | 0.80 | GBA1 (0.40) | ALDH1A1PKMNPY5R | |
| SCHEMBL3885136 | 0.79 | HTR4 (0.37) | HTR4F10HRH3ALDH1A1METAP2 | |
| SCHEMBL10232790 | 0.79 | XPNPEP1 (0.36) | HTR4HRH3ALDH1A1PKMMETAP2 | |
| SCHEMBL220468 | 0.78 | F10 (0.48) | F10HRH3ALDH1A1 | |
| SCHEMBL24837283 | 0.76 | HTR4 (0.35) | HTR4F10HRH3ALDH1A1PKM | |
| SCHEMBL3363470 | 0.75 | CYP2D6 (0.41) | ALDH1A1 | |
| SCHEMBL4592502 | 0.73 | MAOB (0.50) | HTR4ALDH1A1PKMENPP1 | |
| SCHEMBL3879332 | 0.72 | F10 (0.35) | HTR4F10ALDH1A1 | |
| SCHEMBL17776662 | 0.70 | XPNPEP1 (0.35) | HTR4HRH3ALDH1A1PKMNSD2 | |
| SCHEMBL222294 | 0.70 | F10 (0.46) | F10HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | claimed |
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |