Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935022 | 0.78 | BRD4 (0.34) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL23176145 | 0.72 | PDPK1 (0.36) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL15935018 | 0.70 | MAPT (0.54) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL15923977 | 0.69 | RXRA (0.32) | — | |
| SCHEMBL23175861 | 0.66 | MAPK13 (0.41) | — | |
| SCHEMBL15923550 | 0.66 | MAPT (0.34) | — | |
| SCHEMBL19132920 | 0.65 | KDM4E (0.44) | — | |
| SCHEMBL24920862 | 0.65 | MAPT (0.34) | — | |
| SCHEMBL24142971 | 0.64 | PDE10A (0.41) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL12126182 | 0.64 | PTGS2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934538-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2021-03-31 | — | — | EP | disclosed |