Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921233 | 0.80 | CCR1 (0.44) | MAPTALDH1A1CCR1CCR5CCR8 | |
| SCHEMBL30740344 | 0.76 | TRPV1 (0.39) | TDO2EGLN1GRM5GRM4 | |
| SCHEMBL31346256 | 0.76 | TDO2 (0.35) | TDO2GRM5GRM4 | |
| SCHEMBL24921962 | 0.75 | TDO2 (0.34) | GRIN1GRIN2BTDO2RXRAEGLN1 | |
| SCHEMBL15935022 | 0.75 | BRD4 (0.34) | MAPK14CYP1A2GRIN1GRIN2BCYP2C19 | |
| SCHEMBL24920900 | 0.74 | PDK2 (0.35) | CYP1A2CYP2C19CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL24921183 | 0.74 | MAP4K1 (0.41) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL15923977 | 0.74 | RXRA (0.32) | GRIN1GRIN2BRXRA | |
| SCHEMBL19132920 | 0.73 | KDM4E (0.44) | MAPTCYP1A2GRIN1GRIN2BCYP2C19 | |
| SCHEMBL24920785 | 0.73 | ALKBH1 (0.41) | GRIN1GRIN2BTDO2RXRAGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |