Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935406 | 0.83 | AR (0.46) | MAPTL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL23176129 | 0.79 | MAPT (0.35) | MAPTL3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15924577 | 0.70 | AR (0.44) | MAPTALDH1A1KDM4EHPGDAR | |
| SCHEMBL15825596 | 0.70 | AR (0.44) | MAPTALDH1A1KDM4EHPGDAR | |
| SCHEMBL583927 | 0.69 | MEN1 (0.46) | MAPTL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL19068634 | 0.69 | AR (0.43) | ALDH1A1NPSR1KDM4EHPGDAR | |
| SCHEMBL15832410 | 0.68 | AR (0.45) | MAPTALDH1A1GAAKDM4EHPGD | |
| SCHEMBL15832233 | 0.67 | ALDH1A1 (0.43) | MAPTL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12852584 | 0.67 | ALOX15 (0.50) | MAPTL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3325578 | 0.66 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934538-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2021-03-31 | — | — | EP | disclosed |