Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13519613 | 1.00 | DRD2 (0.35) | DRD2DRD3KMT2AACHESLC2A1 | |
| SCHEMBL2315477 | 0.93 | DRD2 (0.34) | DRD2DRD3KMT2APOLBHTR1A | |
| SCHEMBL12433051 | 0.93 | DRD2 (0.34) | DRD2DRD3KMT2APOLBHTR1A | |
| SCHEMBL2317120 | 0.91 | MCHR1 (0.34) | DRD2DRD3KMT2AACHESLC2A1 | |
| SCHEMBL12432704 | 0.90 | DRD2 (0.36) | DRD2DRD3KMT2AACHEPOLB | |
| SCHEMBL12433054 | 0.84 | DRD2 (0.41) | DRD2DRD3KMT2AACHEPOLB | |
| SCHEMBL2321347 | 0.84 | DRD2 (0.41) | DRD2DRD3KMT2AACHEPOLB | |
| SCHEMBL2321394 | 0.84 | PTGIR (0.31) | DRD2DRD3 | |
| SCHEMBL2319128 | 0.84 | KMT2A (0.39) | DRD2DRD3KMT2APOLBHTR1A | |
| SCHEMBL13519606 | 0.84 | KMT2A (0.39) | DRD2DRD3KMT2APOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | claimed |
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | disclosed |