Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317120 | 0.93 | MCHR1 (0.34) | DRD2DRD3 | |
| SCHEMBL12433051 | 0.90 | DRD2 (0.34) | PTGIRDRD2HTR2ADRD3 | |
| SCHEMBL2315477 | 0.90 | DRD2 (0.34) | PTGIRDRD2HTR2ADRD3 | |
| SCHEMBL2321353 | 0.88 | GUCY1B2 (0.31) | — | |
| SCHEMBL2314265 | 0.86 | GRM4 (0.33) | — | |
| SCHEMBL2317618 | 0.84 | DRD2 (0.35) | DRD2DRD3 | |
| SCHEMBL13519613 | 0.84 | DRD2 (0.35) | DRD2DRD3 | |
| SCHEMBL2316451 | 0.84 | SRD5A2 (0.30) | — | |
| SCHEMBL2313919 | 0.83 | SIGMAR1 (0.33) | DRD2DRD3 | |
| SCHEMBL2314368 | 0.82 | THRB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | claimed |