SCHEMBL23176239

SCHEMBL23176239

Cc1cnnc2ccnn12

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.33
DGAT1 O75907 3/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4572140 0.70 DGAT1 (0.37) PDE10ADGAT1MEN1KMT2A
SCHEMBL3460690 0.67 PIK3CG (0.48) PDE10A
SCHEMBL84692 0.67 MKNK1 (0.53) PDE10ADGAT1
SCHEMBL23175771 0.67
SCHEMBL20664459 0.64 PDE10A (0.43) PDE10A
SCHEMBL13073900 0.64 PDE10A (0.43) PDE10A
SCHEMBL9300367 0.64 PDE10A (0.43) PDE10A
SCHEMBL266452 0.62 DGAT1 (0.41) PDE10ADGAT1
SCHEMBL24284154 0.62 PDE10A (0.34) PDE10A
SCHEMBL85350 0.62 NOTUM (0.34) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021058595-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-04-01 WO disclosed