Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613256 | 1.00 | P2RX4 (0.40) | P2RX4NPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29613253 | 0.86 | MAPT (0.39) | P2RX4NPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23178258 | 0.86 | MAPT (0.39) | P2RX4NPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29613266 | 0.67 | HSD11B1 (0.39) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23178110 | 0.67 | HTT (0.35) | P2RX4MEN1KMT2ATSHRMAPT | |
| SCHEMBL29613271 | 0.67 | HTT (0.35) | P2RX4MEN1KMT2ATSHRMAPT | |
| SCHEMBL23178256 | 0.67 | HSD11B1 (0.39) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23178101 | 0.66 | HTT (0.34) | P2RX4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL23178257 | 0.66 | MAPT (0.35) | P2RX4MEN1KMT2AMAPK1MAPT | |
| SCHEMBL23178307 | 0.66 | P2RX4 (0.33) | P2RX4MEN1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220333004-A1 | Dihydroquinoline Photochromic Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2022-10-20 | — | — | US | disclosed |
| WO-2021058114-A1 | DIHYDROQUINOLINE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, LTD. (IE) | 2021-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220333004-A1 | Dihydroquinoline Photochromic Compounds | CBR3, CBR1, RECQL | P2RX4 1173/4885NPSR1 1634/4885CYP1A2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.