Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285100 | 0.89 | GAA (0.50) | KDM4EEPHX1ALDH1A1LMNAHPGD | |
| SCHEMBL2016900 | 0.83 | LMNA (0.48) | KDM4EEPHX1ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL2018001 | 0.82 | LMNA (0.47) | KDM4EEPHX1ALDH1A1LMNAHPGD | |
| SCHEMBL24330250 | 0.79 | EPHX2 (0.55) | EPHX1KMT2AMEN1GNAI3GNAO1 | |
| SCHEMBL11682924 | 0.78 | MTNR1A (0.50) | EPHX1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL256673 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28162204 | 0.76 | — | — | |
| SCHEMBL25447787 | 0.76 | LMNA (0.55) | EPHX1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL5988081 | 0.74 | — | — | |
| SCHEMBL20581686 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1HPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021058024-A1 | LSD1 INHIBITOR | 南京明德新药研发有限公司 | 2021-04-01 | — | — | WO | disclosed |