SCHEMBL12285100

SCHEMBL12285100

CCCCNCC(=O)NC1CC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
DPP4 P27487 1/20 0.46
GNAI3 P08754 1/20 0.45
GNAO1 P09471 1/20 0.45
GNAI1 P63096 1/20 0.45
KDM4E B2RXH2 1/20 0.44
EPHX1 P07099 7/20 0.44
EPHX2 P34913 2/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23178175 0.89 KDM4E (0.47) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL2016900 0.80 LMNA (0.48) GAAMEN1ALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL2018001 0.79 LMNA (0.47) GAAMEN1ALDH1A1MAPTHPGD
SCHEMBL3309908 0.76 MEN1 (0.65) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL24330250 0.76 EPHX2 (0.55) MEN1KMT2AGNAI3GNAO1GNAI1
SCHEMBL11682924 0.75 MTNR1A (0.50) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL256673 0.75
SCHEMBL3551415 0.75 GNAI3 (0.72) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL5313764 0.74 GAA (0.58) GAAMEN1ALDH1A1KMT2ADPP4
Hydrochloric Acid SCHEMBL28162204 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110263604-A1 Oxidase inhibitors and their use ORYZON GENOMICS, S.A. (ES) 2011-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263604-A1 Oxidase inhibitors and their use MAOA, PNPO, MAOB GAA 382/4885MEN1 4506/4885ALDH1A1 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.