Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783646 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTNPSR1PRNPRXFP1 | |
| SCHEMBL2320914 | 0.81 | NPC1 (0.34) | ALDH1A1MAPTNPC1RAB9ACYP1A1 | |
| SCHEMBL19783129 | 0.79 | CYP11B1 (0.40) | ALDH1A1MAPTNPSR1PRNPRXFP1 | |
| Hydrochloric Acid SCHEMBL28941261 | 0.78 | CYP11B1 (0.39) | ALDH1A1MAPTNPSR1PRNPRXFP1 | |
| SCHEMBL19776271 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPTNPSR1PRNPRXFP1 | |
| SCHEMBL19776334 | 0.76 | MAPT (0.39) | ALDH1A1MAPTNPSR1PRNPRXFP1 | |
| SCHEMBL2319227 | 0.75 | LMNA (0.33) | NPSR1PRNPNQO2HPGD | |
| SCHEMBL19776056 | 0.75 | ALDH1A1 (0.35) | ALDH1A1MAPTNPSR1PRNPRXFP1 | |
| SCHEMBL23796376 | 0.74 | KDM4E (0.49) | KDM4E | |
| SCHEMBL23795961 | 0.73 | PSMD14 (0.50) | ALDH1A1MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440595-B2 | Fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-05-14 | — | — | US | disclosed |
| EP-2185519-B1 | NOVEL FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-10 | — | — | EP | disclosed |
| US-20100286199-A1 | NOVEL FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| CN-101815703-A | Novel fungicides | SYNGENTA PARTICIPATIONS AG | 2010-08-25 | — | — | CN | disclosed |
| EP-2185519-A2 | NOVEL FUNGICIDES | Sygenta Participations AG. (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009049716-A2 | NOVEL FUNGICIDES | SYGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286199-A1 | NOVEL FUNGICIDES | CYP51A1, CYP4X1, CYP1B1 | ALDH1A1 262/4885MAPT 4059/4885NPSR1 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.