Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575 | 0.99 | ACHE (0.44) | ACHELTB4R2FFAR1AKR1B1OXTR | |
| SCHEMBL3375483 | 0.86 | ACHE (0.47) | ACHELTB4R2OXTRAVPR1AAGTR1 | |
| SCHEMBL27191042 | 0.82 | LTB4R2 (0.41) | ACHELTB4R2AGTR1ITGB1ITGA4 | |
| SCHEMBL3077 | 0.81 | LTB4R2 (0.44) | LTB4R2AGTR1 | |
| SCHEMBL1993 | 0.80 | LTB4R2 (0.45) | LTB4R2AGTR1 | |
| SCHEMBL21083703 | 0.80 | LTB4R2 (0.41) | ACHELTB4R2FFAR1AKR1B1AGTR1 | |
| SCHEMBL2366 | 0.79 | LTB4R2 (0.47) | ACHELTB4R2FFAR1AKR1B1OXTR | |
| SCHEMBL21083532 | 0.78 | LTB4R2 (0.47) | ACHELTB4R2AGTR1 | |
| SCHEMBL21083851 | 0.78 | LTB4R2 (0.45) | ACHELTB4R2AGTR1 | |
| SCHEMBL29726839 | 0.78 | LTB4R2 (0.45) | ACHELTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |