Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911 | 0.99 | LTB4R2 (0.48) | LTB4R2ACHEOXTRAVPR1AAGTR1 | |
| SCHEMBL8484079 | 0.91 | LTB4R2 (0.40) | LTB4R2ACHEOXTRAVPR1AAGTR1 | |
| SCHEMBL7270209 | 0.87 | LTB4R2 (0.45) | LTB4R2ACHEOXTRAVPR1AAGTR1 | |
| SCHEMBL8484799 | 0.84 | LTB4R2 (0.34) | LTB4R2ACHEOXTRAVPR1A | |
| SCHEMBL3101 | 0.84 | ACHE (0.41) | LTB4R2ACHEOXTRAVPR1AAGTR1 | |
| SCHEMBL8487085 | 0.84 | LTB4R2 (0.36) | LTB4R2ACHEAGTR1 | |
| SCHEMBL8487248 | 0.83 | LTB4R2 (0.34) | LTB4R2ACHEOXTRAVPR1A | |
| SCHEMBL8911282 | 0.83 | LTB4R2 (0.34) | LTB4R2ACHEOXTRAVPR1AAGTR1 | |
| SCHEMBL2445 | 0.81 | LTB4R2 (0.53) | LTB4R2OXTRAVPR1AAGTR1FFAR1 | |
| SCHEMBL682687 | 0.81 | AGTR1 (0.47) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |