Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 3/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25052999 | 0.79 | SIRT2 (0.51) | SIRT2SIRT1SIRT3TLR2SIRT5 | |
| SCHEMBL22452312 | 0.77 | SIRT2 (0.44) | SIRT2SIRT1SIRT3MMP3SIRT5 | |
| SCHEMBL26283842 | 0.73 | CPB1 (0.49) | SIRT2SIRT1SIRT3MMP3SIRT5 | |
| SCHEMBL26281010 | 0.72 | CPB1 (0.47) | SIRT2SIRT1SIRT3MMP3SIRT5 | |
| SCHEMBL25100592 | 0.70 | SIRT2 (0.42) | SIRT2SIRT1SIRT3MMP3TLR2 | |
| SCHEMBL24774073 | 0.70 | KLKB1 (0.44) | SIRT2SIRT1EPORTLR2SIRT5 | |
| SCHEMBL26279273 | 0.69 | SIRT2 (0.44) | SIRT2SIRT1SIRT3MMP3SIRT5 | |
| SCHEMBL25839420 | 0.69 | SIRT2 (0.38) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL23425577 | 0.69 | KLKB1 (0.45) | SIRT2SIRT1TLR2 | |
| SCHEMBL17090699 | 0.68 | KLKB1 (0.46) | SIRT2SIRT1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797796-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | Mabplex International, Ltd. (CN) | 2021-03-31 | — | — | EP | disclosed |