Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25052999 | 0.84 | SIRT2 (0.51) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL23180461 | 0.77 | SIRT2 (0.36) | SIRT2SIRT1MMP3SIRT3SIRT5 | |
| SCHEMBL25100592 | 0.77 | SIRT2 (0.42) | SIRT2SIRT1KLKB1MMP3PDF | |
| SCHEMBL26283842 | 0.77 | CPB1 (0.49) | SIRT2SIRT1KLKB1MMP3SIRT3 | |
| SCHEMBL24906651 | 0.77 | SIRT1 (0.45) | SIRT2SIRT1KLKB1MMP3PDF | |
| SCHEMBL24390289 | 0.77 | SIRT1 (0.45) | SIRT2SIRT1KLKB1MMP3PDF | |
| SCHEMBL26017200 | 0.77 | MMP3 (0.43) | SIRT2SIRT1KLKB1LTA4HMMP3 | |
| SCHEMBL17090699 | 0.76 | KLKB1 (0.46) | SIRT2SIRT1KLKB1LTA4HMMP3 | |
| SCHEMBL25932588 | 0.76 | LTA4H (0.41) | SIRT2SIRT1KLKB1LTA4HMMP3 | |
| SCHEMBL14821040 | 0.76 | SSTR3 (0.55) | SIRT2SIRT1LTA4HMMP3SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107560-A1 | DLK1 ANTIBODIES AND METHODS OF TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2020191344-A1 | CLAUDIN-6 BISPECIFIC ANTIBODIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020191342-A1 | CLAUDIN-6 ANTIBODIES AND DRUG CONJUGATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-24 | — | — | WO | disclosed |