Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27084872 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL24696800 | 0.84 | MTNR1A (0.64) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL27085124 | 0.84 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL23181298 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL27084981 | 0.79 | MTNR1A (0.81) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL30630306 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL4490583 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL27085225 | 0.78 | MTNR1A (0.62) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL30630322 | 0.78 | MTNR1A (0.62) | MTNR1AMTNR1BCYP1A2HPGDMEN1 | |
| SCHEMBL25101193 | 0.76 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220390454-A1 | BIOMARKER PANEL TARGETED TO DISEASES DUE TO MULTIFACTORIAL ONTOLOGY OF GLYCOCALYX DISRUPTION | ARTEREZ, INC. (US) | 2022-12-08 | — | — | US | disclosed |
| WO-2021062298-A1 | BIOMARKER PANEL TARGETED TO DISEASES DUE TO MULTIFACTORIAL ONTOLOGY OF GLYCOCALYX DISRUPTION | ARTEREZ, INC. (US) | 2021-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220390454-A1 | BIOMARKER PANEL TARGETED TO DISEASES DUE TO MULTIFACTORIAL ONTOLOGY OF GLYCOCALYX DISRUPTION | SDCBP, LGALS2, SDC1 | MTNR1A 3988/4885MTNR1B 3697/4885CYP1A2 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.