Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987572 | 0.81 | MAOA (0.43) | MAOAKMT2AL3MBTL1NOX1MEN1 | |
| SCHEMBL15956985 | 0.81 | MAOA (0.43) | MAOAKMT2AL3MBTL1NOX1MEN1 | |
| SCHEMBL3148112 | 0.81 | MAOA (0.43) | MAOAKMT2AL3MBTL1NOX1MEN1 | |
| Hydrochloric Acid SCHEMBL15957113 | 0.79 | MAOA (0.42) | MAOAKMT2AL3MBTL1NOX1MEN1 | |
| Hydrochloric Acid SCHEMBL15957112 | 0.79 | MAOA (0.42) | MAOAKMT2AL3MBTL1NOX1MEN1 | |
| SCHEMBL23188831 | 0.71 | MTNR1A (0.33) | MAOAADRA2CAADATGOT1KYAT1 | |
| SCHEMBL23189076 | 0.69 | MAOA (0.44) | MAOAKMT2ANOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL14387511 | 0.68 | RIPK1 (0.40) | MAOAKMT2AL3MBTL1NOX1MEN1 | |
| SCHEMBL10061098 | 0.67 | MAOA (0.41) | MAOAKMT2ANOTUMHSD17B3ALDH1A1 | |
| SCHEMBL18391837 | 0.66 | NOTUM (0.40) | MAOAKMT2ANOX1NOTUMHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2021-04-07 | — | — | EP | disclosed |