Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287022 | 1.00 | LMNA (0.64) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL19287004 | 1.00 | LMNA (0.64) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL19788359 | 1.00 | LMNA (0.64) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL24688360 | 1.00 | LMNA (0.64) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL19788349 | 1.00 | LMNA (0.64) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL24919805 | 1.00 | LMNA (0.64) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL19788324 | 1.00 | LMNA (0.64) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL21210737 | 0.98 | LMNA (0.61) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL19788360 | 0.98 | LMNA (0.61) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL18897297 | 0.98 | LMNA (0.60) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230276788-A1 | COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION | X-THERMA, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20210100238-A1 | COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION | X-THERMA, INC. (US) | 2021-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210100238-A1 | COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION | CUTA, IAPP, CRYAA | LMNA 670/4885CYP2D6 4658/4885SPHK1 3673/4885 |
| US-20230276788-A1 | COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION | CUTA, IAPP, CRYAA | LMNA 670/4885CYP2D6 4658/4885SPHK1 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.