Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317964 | 0.83 | EPRS1 (0.40) | LMNACACNA1HEPRS1 | |
| SCHEMBL2318935 | 0.79 | EGLN1 (0.47) | NOTUMKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL11369909 | 0.75 | CFTR (0.37) | NOTUMKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL19742259 | 0.74 | CACNA1H (0.46) | ALDH1A1CACNA1HEPRS1 | |
| SCHEMBL12020667 | 0.74 | MAPT (0.41) | KDM4EALDH1A1HTTMAPTCACNA1H | |
| SCHEMBL19742260 | 0.73 | EPRS1 (0.34) | NOTUMCFTREPRS1 | |
| SCHEMBL27347629 | 0.72 | NOTUM (0.60) | NOTUMLMNAHTTCFTRSOS1 | |
| SCHEMBL13748011 | 0.71 | MMP2 (0.50) | ALDH1A1L3MBTL1HTTMMP2MMP9 | |
| SCHEMBL2319832 | 0.69 | CSNK2A1 (0.33) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL31568995 | 0.68 | MAPT (0.44) | KDM4EALDH1A1LMNAMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097491-A1 | BENZIMIDAZOLE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-08-11 | — | — | WO | disclosed |