Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPRS1 | P07814 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319088 | 0.83 | NOTUM (0.46) | EPRS1LMNACACNA1H | |
| SCHEMBL17109179 | 0.80 | PIN1 (0.40) | PIN1LMNAEGLN1 | |
| SCHEMBL19742259 | 0.79 | CACNA1H (0.46) | EPRS1SMN1; SMN2EGLN1CACNA1H | |
| SCHEMBL2322551 | 0.78 | RBP4 (0.35) | PIN1SMN1; SMN2EGLN1CACNA1H | |
| SCHEMBL19742260 | 0.77 | EPRS1 (0.34) | EPRS1HCAR1 | |
| SCHEMBL21906383 | 0.77 | RXRA (0.43) | PIN1LMNAEGLN1RXRARXRB | |
| SCHEMBL12020667 | 0.75 | MAPT (0.41) | SMN1; SMN2CACNA1HHCAR1 | |
| SCHEMBL3689256 | 0.74 | ERN1 (0.45) | PIN1SMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL2319832 | 0.73 | CSNK2A1 (0.33) | HCAR1 | |
| SCHEMBL20495249 | 0.70 | S1PR1 (0.39) | PIN1SMN1; SMN2LMNAEGLN1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097491-A1 | BENZIMIDAZOLE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-08-11 | — | — | WO | disclosed |