SCHEMBL2319151

SCHEMBL2319151

COc1ccc(C2Oc3cc(O)cc(O)c3CC2=O)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.57
CYP1A1 P04798 3/20 0.57
CYP1A2 P05177 3/20 0.57
CYP1B1 Q16678 3/20 0.57
TP53 P04637 2/20 0.57
CYP3A4 P08684 2/20 0.57
XDH P47989 2/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
PKM P14618 1/20 0.57
NPC1 O15118 1/20 0.57
CA12 O43570 1/20 0.57
KDM1A O60341 1/20 0.57
ALDH1A1 P00352 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
TSHR P16473 1/20 0.57
CA4 P22748 1/20 0.57
DPP4 P27487 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14829729 0.92 CYP19A1 (0.52) CYP19A1CYP1A1CYP1A2CYP1B1TP53
SCHEMBL6509060 0.92 CYP1A1 (0.56) CYP19A1CYP1A1CYP1A2CYP1B1TP53
Hesperetin SCHEMBL20164911 0.88 CYP19A1 (0.79) CYP19A1CYP1A1CYP1A2CYP1B1TP53
Hesperetin SCHEMBL5202127 0.88 CYP19A1 (0.79) CYP19A1CYP1A1CYP1A2CYP1B1TP53
SCHEMBL18339272 0.87 CYP19A1 (0.45) CYP19A1CYP1A1CYP1A2CYP1B1TP53
SCHEMBL27205452 0.87 CYP19A1 (0.45) CYP19A1CYP1A1CYP1A2CYP1B1TP53
SCHEMBL7200862 0.86 CYP1A1 (0.54) CYP19A1CYP1A1CYP1A2CYP1B1TP53
SCHEMBL16151244 0.86 KDM4E (0.54) CYP19A1CYP1A1CYP1A2CYP1B1TP53
SCHEMBL2781922 0.86 KDM4E (0.54) CYP19A1CYP1A1CYP1A2CYP1B1TP53
SCHEMBL8249167 0.86 KDM4E (0.54) CYP19A1CYP1A1CYP1A2CYP1B1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180042962-A1 Vascular Calcification Prevention and Treatment Summit Innovation Labs LLC (US) 2018-02-15 US claimed
EP-0290442-A4 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. CHEMEX PHARMACEUTICALS INC (US) 1990-07-03 EP claimed
EP-0290442-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-11-17 EP claimed
WO-1988003805-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-06-02 WO claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed
US-20250114424-A1 PLANT EXTRACT-BASED COMPOSITION AND ITS USE FOR TREATING GLUCOSE METABOLISM DISORDERS ESSERRE PHARMA SRL (IT) 2025-04-10 US disclosed
EP-3496844-B1 VASCULAR CALCIFICATION AND CARDIOVASCULAR/ASSOCIATED DISEASES PREVENTION AND TREATMENT Summit Innovation Labs LLC (US) 2024-03-13 EP disclosed
WO-2023012283-A1 PLANT EXTRACT-BASED COMPOSITION AND ITS USE FOR TREATING GLUCOSE METABOLISM DISORDERS ESSERRE PHARMA SRL (IT) 2023-02-09 WO disclosed
US-11357250-B2 Treatment and prevention of diabetes and obesity Summit Innovation Labs LLC (US) 2022-06-14 US disclosed
US-11344575-B2 Vascular calcification prevention and treatment Summit Innovation Labs, LLC (US) 2022-05-31 US disclosed
US-11234918-B2 Methods for botanical and/or algae extraction BASF CORPORATION (US) 2022-02-01 US disclosed
US-11039636-B2 Treatment and prevention of bone and joint disorders Summit Innovation Labs, LLC (US) 2021-06-22 US disclosed
US-5885969-A INCREASING WATER SOLUBILITY AND PREVENTING CRYSTALS PRECIPITATION IN CANNED TANGERINES, ALSO PREVENT THE FADING OF NATURAL COLORING AGENTS; STORAGE STABILITY KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1999-03-23 US disclosed
WO-1998036750-A1 ANTI-MICROBIAL PRODUCT BTG INTERNATIONAL LIMITED (GB) 1998-08-27 WO disclosed
EP-0825196-A2 Enzyme-treated hesperidin, process for producing the same and method of using enzyme-treated hesperidin Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 1998-02-25 EP disclosed
EP-0290442-A4 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. CHEMEX PHARMACEUTICALS INC (US) 1990-07-03 EP disclosed
EP-0290442-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-11-17 EP disclosed
WO-1988003805-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-06-02 WO disclosed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US disclosed
EP-0065123-B1 HARDLY SOLUBLE SALTS OF AMINOGLYCOSIDE ANTIBIOTICS MERCK PATENT GmbH (DE) 1984-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11234918-B2 Methods for botanical and/or algae extraction ALG1, ALG8, CUTA CYP19A1 1745/4885CYP1A1 2372/4885CYP1A2 2550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.