Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | BACE1 | P56817 | 6/20 | 0.54 |
| ▸ | RECQL | P46063 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | APEX1 | P27695 | 3/20 | 0.54 |
| ▸ | ALPL | P05186 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | SNCA | P37840 | 3/20 | 0.54 |
| ▸ | ALPG | P10696 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16151244 | 1.00 | KDM4E (0.54) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL2781922 | 1.00 | KDM4E (0.54) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL349722 | 0.89 | CYP3A4 (0.52) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL3487578 | 0.89 | CYP3A4 (0.52) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL2319151 | 0.86 | CYP19A1 (0.57) | HSD17B10MAPTPKMPOLBCYP3A4 | |
| SCHEMBL6503937 | 0.86 | CYP19A1 (0.49) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL15544306 | 0.86 | RECQL (0.56) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL28616927 | 0.85 | RECQL (0.44) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL7809366 | 0.85 | CYP19A1 (0.45) | KDM4EBACE1RECQLGAAHSD17B10 | |
| SCHEMBL29282180 | 0.85 | CYP19A1 (0.45) | KDM4EBACE1RECQLGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002877-A1 | PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES | MARS, INCORPORATED (US) | 2007-01-04 | — | — | WO | disclosed |