Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CBS | P35520 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27974387 | 0.94 | CYP19A1 (0.47) | CYP1A1CYP1A2CYP1B1POLBMAPT | |
| SCHEMBL3368235 | 0.89 | CYP19A1 (0.53) | CYP1A1CYP1A2CYP1B1MAPTCBS | |
| SCHEMBL3487578 | 0.87 | CYP3A4 (0.52) | CYP1A1CYP1A2CYP1B1POLBMAPT | |
| SCHEMBL349722 | 0.87 | CYP3A4 (0.52) | CYP1A1CYP1A2CYP1B1POLBMAPT | |
| SCHEMBL2319151 | 0.86 | CYP19A1 (0.57) | CYP1A1CYP1A2CYP1B1POLBMAPT | |
| SCHEMBL6509060 | 0.85 | CYP1A1 (0.56) | CYP1A1CYP1A2CYP1B1POLBMAPT | |
| SCHEMBL3364490 | 0.85 | ABCG2 (0.54) | MAPTCYP19A1ALDH1A1CYP3A4ATM | |
| SCHEMBL27830643 | 0.85 | ALOX15 (0.45) | CYP1A1CYP1A2CYP1B1POLBMAPT | |
| SCHEMBL6503937 | 0.84 | CYP19A1 (0.49) | POLBMAPTKMT2ARECQLMEN1 | |
| SCHEMBL14829729 | 0.83 | CYP19A1 (0.52) | CYP1A1CYP1A2CYP1B1MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617293-A | Flavonoid phosphate salts of aminoglycoside antibiotics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | claimed |
| EP-1286706-A2 | GAMMA IRRADIATION OF PROTEIN-BASED PHARMACEUTICAL PRODUCTS | The American National Red Cross (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087357-A2 | GAMMA IRRADIATION OF PROTEIN-BASED PHARMACEUTICAL PRODUCTS | THE AMERICAN NATIONAL RED CROSS (US) | 2001-11-22 | — | — | WO | disclosed |
| US-4617293-A | Flavonoid phosphate salts of aminoglycoside antibiotics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | disclosed |
| EP-0065123-B1 | HARDLY SOLUBLE SALTS OF AMINOGLYCOSIDE ANTIBIOTICS | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| EP-0065123-A1 | Hardly soluble salts of aminoglycoside antibiotics | MERCK PATENT GmbH (DE) | 1982-11-24 | — | — | EP | disclosed |