Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIEZO1 | Q92508 | 5/20 | 0.83 |
| ▸ | TERT | O14746 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490578 | 0.91 | PIEZO1 (1.00) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL23195699 | 0.82 | PIEZO1 (0.78) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL23195706 | 0.81 | PIEZO1 (0.81) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL23195760 | 0.79 | PIEZO1 (0.74) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL31520562 | 0.79 | PIEZO1 (0.73) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL31520557 | 0.79 | PIEZO1 (0.73) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL23195769 | 0.79 | PIEZO1 (0.73) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL23195352 | 0.77 | PIEZO1 (0.69) | PIEZO1TERTALDH1A1ATMNPC1 | |
| SCHEMBL6490858 | 0.75 | TERT (0.77) | PIEZO1TERTALDH1A1ATMRAB9A | |
| SCHEMBL23195738 | 0.75 | PIEZO1 (0.67) | PIEZO1TERTALDH1A1ATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067943-A1 | PIEZO1 AGONISTS FOR THE PROMOTION OF BONE FORMATION | BIOVENTURES, LLC (US) | 2021-04-08 | — | — | WO | disclosed |